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Regulation (Biological)

The capacity of biological systems to modulate their component processes in response to changes in internal or external conditions. Often, regulation is achieved by designated subsystems that are partly independent of the dynamics of controlled processes.


Bich, L., Mossio, M., Ruiz-Mirazo, K. and A. Moreno. (2016). “Biological regulation: controlling the system from within.” Biology & Philosophy 31:237–265.

Allied Concepts:
Modularity, Niche construction, Plasticity, Robustness


An entity that passes on its structure largely intact through successive replications.


Hull, D.L. (1980). “Individuality and selection.” Annual Review of Ecology and Systematics 11:311–322.


The ability of a system to maintain its functions and organization despite internal and external perturbations.


Kitano, H. (2004). “Biological robustness.” Nature Reviews Genetics 5(11):826–837.