This mutational hypothesis offers to explain both evolutionary parallelism and recurrence in disease of gene fusions under one umbrella. Here, we test this hypothesis using bioinformatic data. Evgeni Bolotin, Daniel Melamed, and Adi Livnat write in bioRxiv.
This paper has three aims: first, to analyse the organisational conditions and the physiological mechanisms that enable integration in prokaryotic associations; second, to discuss the organisational differences between biofilms and prokaryotic endosymbiosis and the types of integration they achieve; finally, to provide a more precise account of functional integration based on these case studies. Guglielmo Militello, Leonardo Bich and Alvaro Moreno write in Acta Biotheoretica.